Closed-loop administration of propofol for the control of hypnosis in anesthesia has evidenced an outperformance when comparing it with manual administration in terms of drug consumption and post-operative recovery of patients. Unlike other systems, the success of this strategy lies on the availability of a feedback variable capable of quantifying the current hypnotic state of the patient. However, the appearance of anomalies during the anesthetic process may result in inaccurate actions of the automatic controller. These anomalies may come from the (...) monitors, the syringe pumps, the actions of the surgeon or even from alterations in patients. This could produce adverse side effects that can affect the patient postoperative and reduce the safety of the patient in the operating room. Then, the use of anomaly detection techniques plays a significant role to avoid this undesirable situations. This work assesses different one-class intelligent techniques to detect anomalies in patients undergoing general anesthesia. Due to the difficulty of obtaining real data from anomaly situations, artificial outliers are generated to check the performance of each classifier. The final model presents successful performance. (shrink)

The rapid increase of industry-sponsored clinical research towards developing countries has led to potentially complex ethical issues to assess. There is scarce evidence about the perception of these participants about the ethical compliance, security, and protection. We sought to evaluate and contrast the awareness and perception of participants and non-participants of industry-sponsored research trials on ethical, safety, and protection topics. A Cases-control survey conducted at twelve research sites in México. Previous and current participants of ISRT as well as non-participants with (...) one of four chronic diseases, were asked to complete the survey which focused on ethical compliance and protection issues of ISRT, and the perception of participating in a trial. A total of 604 cases and 604 controls were surveyed. Cases significantly answered that ethics committees are aware of what is happening in studies, and that medical care of industry-sponsored research trials is better than their usual medical care. The same proportion of cases and controls thought patients must receive economical reimbursement for participating in a research study. The informed consent of the pharmaceutical clinical trial was fully read by 90.4% of the cases. Most cases were satisfied or very satisfied with their overall study participation. Previous and current participants of industry-sponsored research trials have a more positive attitude towards ethics committees, the quality of medical care of the research trials, and the main purpose of economical reimbursements, when compared to non-participants. (shrink)

La presente nota bibliográfica recopila la ingente obra de José Aldazábal, uno de los liturgistas españoles más fecundos en publicaciones de carácter sobre todo divulgativo, que, durante más de cuarenta años y formando parte del Centro de Pastoral Litúrgica de Barcelona, ha acompañado la pastoral litúrgica especialmente en España, pero también en los paísesiberoamericanos de lengua española. Interesará a los investigadores de la historia de la renovación litúrgica y a los estudiosos de la pastoral.

The certainty that natural phenomena and processes could be represented in a physical space ruled by Euclidean geometry was a fundamental epistemological assumption of theoretical creation in classical science. The possibility of a mathematical analysis of the continuum ensured an intuitive, pictorial description of mobile trajectories as studied in dynamics, as well as a precise determination of the effects generated within causal relations. These convictions and assumptions had to be reviewed when the Plank action quantum forced the development of a (...) new physics of atomic systems. Consequences, nevertheless, transcended the scope of Physics and extended to all regions of natural science, including Biology, which had to be built under the conceptual coverage of the nascent mechanics. The present work is a reflection on the philosophical problems posed by the encounter of physics of atoms and chemistry of molecules. (shrink)

El artículo es un breve análisis del discurso de Santiago Ramón y Cajal titulado Psicología de Don Quijote y el quijotismo, un texto poco conocido que fue una de las piezas principales producida en torno al tema con motivo del III centenario del Quijote. El discurso de Ramón y Cajal le fue encargado por el Colegio Médico de San Carlos, y se pronunció en Madrid el día 9 de Mayo de 1905. Las ediciones existentes contienen algunas erratas e inexactitudes. Nuestro (...) análisis expone las ideas de Ramón y Cajal en relación con la situación de la ciencia española y con los remedios que es necesario poner en práctica y con el espíritu que debe animarlos para poner luego en relación las ideas de Ramón y Cajal con las de Unamuno y Ortega, los dos principales autores españoles que escribieron sobre el tema en aquellos mismos años, subrayando la coincidencia entre Unamuno y Ramón y Cajal y la llamativa distancia de Ortega con las ideas de nuestro histólogo en relación con la ciencia. (shrink)

The certainty that natural phenomena and processes could be represented in a physical space ruled by Euclidean geometry was a fundamental epistemological assumption of theoretical creation in classical science. The possibility of a mathematical analysis of the continuum ensured an intuitive, pictorial description of mobile trajectories as studied in dynamics, as well as a precise determination of the effects generated within causal relations. These convictions and assumptions had to be reviewed when the Plank action quantum forced the development of a (...) new physics of atomic systems. Consequences, nevertheless, transcended the scope of Physics and extended to all regions of natural science, including Biology, which had to be built under the conceptual coverage of the nascent mechanics. The present work is a reflection on the philosophical problems posed by the encounter of physics of atoms and chemistry of molecules. (shrink)

This paper approaches the discussion that took place during the second half of the Twentieth Century about the biological significance of the cryptobiotic state. Cryptobiosis has been defined as an evolutionary strategy in which organisms overcome adverse environmental conditions by entering a latency mode considered the third state between life and death. It is a poorly known phenomenon where metabolism, growth, reproduction and senescence are greatly reduced or cease temporarily. Since metabolism is conceived as a defining feature of life, it (...) is argued that Cryptobiosis is a kind of temporal death, because metabolic activity sometimes seems to have stopped completely during the cryptobiotic state. In the following pages we deal with the cryptobiotic phase -as understood in the second half of the last Century-, considering two basic references: a case study, the case of group Tardigrada -small animals between a tenth of a millimeter and one millimeter that can survive in extreme conditions entering different states of latency-; and, secondly, the model around Cryptobiosis as recursive hierarchical metabolism proposed by Yair Neuman. (shrink)

La convicción de que los fenómenos y procesos naturales podían ser representados en un espacio físico regido por la geometría euclídea actuó en la ciencia clásica como supuesto epistemológico fundamental de la creación teórica. La posibilidad de un análisis matemático del continuo garantizaba, en efecto, una descripción intuitiva y pictórica de las trayectorias de los móviles estudiadas por la dinámica, así como una determinación precisa de los efectos producidos en el seno de las relaciones causales. Fueron convicciones y supuestos que (...) tuvieron que ser revisados en el momento en que el cuanto de acción de Planck obligó a desarrollar una nueva... física de los sistemas atómicos. Las consecuencias, no obstante, se dejarían sentir no sólo en el ámbito de la Física sino en todas aquellas regiones de la ciencia natural, como la Biología, que tenían que construirse bajo la cobertura conceptual de la naciente mecánica. El presente trabajo es una reflexión sobre los problemas filosóficos planteados en el encuentro entre la física del átomo y la química de las moléculas. The certainty that natural phenomena and processes could be represented in a physical space ruled by Euclidean geometry was a fundamental epistemological assumption of theoretical creation in classical science. The possibility of a mathematical analysis of the continuum ensured an intuitive, pictorial description of mobile trajectories as studied in dynamics, as well as a precise determination of the effects generated within causal relations. These convictions and assumptions had to be reviewed when the Plank action quantum forced the development of a new physics of atomic systems. Consequences, nevertheless, transcended the scope of Physics and... extended to all regions of natural science, including Biology, which had to be built under the conceptual coverage of the nascent mechanics. The present work is a reflection on the philosophical problems posed by the encounter of physics of atoms and chemistry of molecules. (shrink)

This study explores the micro-determinants of corruption tolerance among 1414 university students in Guatemala, a country grappling with significant corruption issues. By examining the attitudes of economics majors compared to students in other disciplines through ordered logistic regression analysis, we offer new insights into factors influencing corruption tolerance in a developing country setting. This approach, by focusing on a developing country, fills a research gap in the literature on the differences between economics students and their peers from other programs. We (...) find that economics students exhibit a greater tolerance for corruption. This result aligns with theories and research that suggest that economists show a profit-maximizing mindset, and distinctive values and fairness perceptions. Furthermore, our analysis reveals significant effects of gender and age on corruption tolerance, with women and older students reporting lower tolerance to corrupt practices. The study also uncovers the higher tolerance towards private versus public corruption. These findings provide valuable guidance for developing policies and educational initiatives to reduce corruption tolerance among future professionals in similar socio-economic environments. (shrink)

For the sake of universalism and against totalitarianism, discursive ethics has shown with Jürgen Habermas a practical deficit by denying moral philosophy the possibility of reflecting on the alienating conditions for dialogue through a specific ethos. This article examines how Hartmut Rosa's theory of resonance can revitalise the debate on the conditions that can undermine the motivation for dialogue in accelerated societies, based not on the concept of ethos, but on the concept of Modus der Weltbeziehung [Mode of world-relationship]. En (...) aras del universalismo y en contra del totalitarismo, la ética discursiva ha mostrado con Jürgen Habermas un déficit práctico al negar a la filosofía moral la posibilidad de reflexionar sobre las condiciones alienantes del diálogo desde un ethos concreto. El presente artículo analiza el modo en que la teoría de la resonancia formulada por Hartmut Rosa permite revitalizar el debate sobre las condiciones que pueden minar la motivación al diálogo en las sociedades aceleradas sin apoyarse en el concepto de ethos, sino en el de Modus der Weltbeziehung [modo de relacionarse con el mundo]. (shrink)

Manuscript type Empirical. Research question/issue This paper aims to contribute to an improved theoretical and empirical understanding of the role that corporation has to play in anticorruption efforts. Research findings/insights Using cross-country data from three databases (Bribe Payers Index, Corruption Perceptions Index, and Doing Business) we found that pro-bribery Investment Climate conditions in host countries are not related to the payments of bribes by multinational companies when these corporations operate abroad. Theoretical/academic implications After describing the conceptual and policy framework that (...) surrounds the discussion on the role played by firms in anticorruption, we present the current debate regarding the effectiveness of international bribery control instruments, with the World Bank-GAC (2006-2008) report as a basis. Both literature and policy seem to be divided into two main, although not mutually exclusive, positions: one demands improvements in Investment Climate conditions from a joint public-private consensus led by international agencies; the other one supports the effectiveness of self-regulation by firms, independent of Investment Climate improvements. The study provides empirical support to the idea that a better Investment Climate is not enough for reducing corrup tion. Practitioner/policy implications This study offers insights to policy makers interested in promoting the involvement of corporations in the fight against corruption. (shrink)

For several decades, tourism has mainly been identified as an activity that helps people escape their everyday routines, contributes to understanding between cultures, and promotes economic wellbeing. These assumptions have been questioned in both the public sphere and academic research, however. In this context, tourism research is increasingly drawing on ethical frameworks to support its criticism of tourism. Some of the most outstanding research on this issue is by Dean MacCannell, Emeritus Professor at the University of California at Davis and (...) author of one of the seminal works of the social theory of tourism: The Tourist: A New Theory of the Leisure Class (1976). MacCannell examines the moral and ethical aspects of tourism in all his writing, but they are the focal point of his book The Ethics of Sightseeing (2011), in which he identifies the tourists’ responsibility to mediate between their understanding of their own pleasure and the ethical repercussions of the late modern imperative, “Enjoy!”. During the Touriscape congress in Malaga, Spain, in February 2018, MacCannell talked about ethics and tourism with José Luis López, who prepared this interview for Recerca. (shrink)

El entorno digital constituye el nuevo escenario en que se ha de desarrollar la investigación, la lectura y la escritura en el futuro. Su naturaleza, profundamente distinta de la que es propia del entorno que se creó con la imprenta, modificará con toda seguridad las formas de trabajo de los autores y estudiosos, las prácticas intelectuales y la manera en la que se argumentan las distintas exposiciones. La escritura y la lectura son actividades humanas que, debido a su ejercicio ya (...) inmemorial, nos han hecho olvidar su condición de invento, de tecnologías, simples pero nada naturales ni espontáneas, como lo prueba el hecho del mucho tiempo que hay que dedicarles en la educación. El entorno digital nos dota, a la vez, de un nuevo escritorio y de un nuevo mercado: aunque aún es pronto para verlo, se están creando nuevas formas de autoría, de escritura y de erudición digital. (shrink)

Este trabajo presenta los aspectos más importantes de las nuevas Directrices de Bautismo de la Archidiócesis de Sevilla situándolas en el contexto histórico teológico en el que maduran y destacando los principales criterios pastorales que utilizan.

Aprender de los griegos es posible, pero solo si partimos de dos bases necesarias: la primera, que nuestro mundo es profundamente distinto al suyo; la segunda, que el pensamiento libre requiere no quedar prisionero de ningún dogma. La forma primitiva de pensar de los griegos es una escuela que nos puede ayudar a desnudar la enorme cantidad de supuestos en los que se apoya la mentalidad contemporánea.

Recientemente se han ido introduciendo progresivamente en el discurso litúrgico dos cuestiones que se relacionan estrechamente con la noción teológica de la Liturgia y con la Pastoral litúrgica en acto: la cuestión del arte de celebrar y la del arte de participar. En esta nota recojo algunas consideraciones sobre ambas cuestiones partiendo de la noción de celebración que privilegia la Constitución de Liturgia.

En este trabajo se presenta el documento de la Conferencia Episcopal Española sobre la Iniciación Cristiana, publicado en noviembre de 1998. Se destacan los aspectos más relevantes desde el punto de vista pastoral y se plantean algunas cuestiones aún por resolver.

Esta nota, que resume una conferencia pronunciada en octubre de 2011 en las Jornadas Nacionales de Liturgia de Barcelona, analiza y estudia la aportación de Sacramentum Caritatis al importante tema de la participación activa de los fieles en la liturgia. El autor concluye, entre otras cosas, que la sutil distinción entre condiciones personales para la participación y la participación misma enriquece el concepto de actuosa participatio acentuando sus dimensiones más hondas desde el punto de vista de la antropología sacramental.

A partir de la distinción entre culto genéricamente religioso y culto cristiano se reflexiona sobre la novedad de la Liturgia cristiana, en cuya naturaleza pesa más la dimensión descendente, o sea, su cualidad de ser actualización, aquí y hoy, del Misterio de Cristo que la dimensión cultual o ascendente, o sea la glorificación de Dios.